76582-61-1

76582-61-1 structure

Name: 3β-Acetoxy-hop-22(29)-ene
Chemical Name: 3β-Acetoxy-hop-22(29)-ene
CAS Number: 76582-61-1
Molecular Formula: C₃₂H₅₂O₂
Molecular Weight: 468.75
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-08-16 11:47:39
Modify Date: 2024-01-14 11:09:05
3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear[1].

Name	3β-Acetoxy-hop-22(29)-ene

Description	3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	IC50: 0.23 μmol/ear (MPO), 5.74 ± 0.49 μM (yeast α-glucosidase)[1]
References	[1]. López-Huerta FA, et al. Hopane-type triterpenes from Cnidoscolus spinosus and their bioactivities. Bioorg Chem. 2020 Jul;100:103919.

Molecular Formula	C₃₂H₅₂O₂
Molecular Weight	468.75