1646321-00-7

1646321-00-7 structure

1646321-00-7 structure

Name: Tomuzotuximab
Chemical Name: Tomuzotuximab
CAS Number: 1646321-00-7
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-02-08 21:34:31
Modify Date: 2024-04-06 12:39:30
Tomuzotuximab (Anti-Human EGFR Recombinant Antibody) is a fully human glycoengineered IgG1 monoclonal antibody against EGFR. Tomuzotuximab has anticancer effects[1].

Name	Tomuzotuximab

Description	Tomuzotuximab (Anti-Human EGFR Recombinant Antibody) is a fully human glycoengineered IgG1 monoclonal antibody against EGFR. Tomuzotuximab has anticancer effects[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
In Vitro	Tomuzotuximab has a fully human glycosylation pattern and is glyco-optimised at its Fc domain, while fully retaining the affinity, specificity, EGFR inhibition and induction of apoptosis of Cetuximab[1].
References	[1]. Waer Fiedler, et al. Phase I study of tomuzotuximab, a glycoengineered therapeutic antibody against the epidermal growth factor receptor, in patients with advanced carcinomas. ESMO Open. 2018 Feb 1;3(2):e000303.

No Any Chemical & Physical Properties