1957235-67-4
1957235-67-4 structure
- Name: Thalidomide-NH-(CH2)2-NH2 TFA
- Chemical Name: N-[2-Aminoethyl] Pomalidomide Trifluoroacetic Acid Salt
- CAS Number: 1957235-67-4
- Molecular Formula: C17H17F3N4O6
- Molecular Weight: 430.34
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2023-02-25 11:37:04
- Modify Date: 2024-04-14 11:01:32
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Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-NH-(CH2)2-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules designed to synthesize small PROTAC molecules targeting SHP2 protein.
| Name | N-[2-Aminoethyl] Pomalidomide Trifluoroacetic Acid Salt |
|---|
| Description | Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-NH-(CH2)2-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules designed to synthesize small PROTAC molecules targeting SHP2 protein. |
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| Related Catalog |
| Melting Point | >224°C (dec.) |
|---|---|
| Molecular Formula | C17H17F3N4O6 |
| Molecular Weight | 430.34 |
| Appearance | Solid | Light Orange to Yellow |
| Storage condition | Hygroscopic, Refrigerator, under inert atmosphere |
| Water Solubility | DMSO (Slightly), Methanol (Slightly) |