2243274-14-6

2243274-14-6 structure

2243274-14-6 structure

Name: Depemokimab
Chemical Name: Depemokimab
CAS Number: 2243274-14-6
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2023-04-05 21:28:26
Modify Date: 2024-04-07 09:40:37
Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma[1][2].

Name	Depemokimab

Description	Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IL-15[1]
In Vivo	Depemokimab (食蟹猴药代动力实验) 与 Mepolizumab (HY-P9945) 相比，清除率降低约 2 倍，IL-5 结合亲和力比 Mepolizumab 高约 30 倍[2]。
References	[1]. Calzetta L, et al. Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma. Biomedicines. 2022 Sep 19;10(9):2330. [2]. Singh D, et al. A Phase 1 study of the long-acting anti-IL-5 monoclonal antibody GSK3511294 in patients with asthma. Br J Clin Pharmacol. 2022 Feb;88(2):702-712.

No Any Chemical & Physical Properties