1189497-48-0

1189497-48-0 structure

Name: Carbamazepine 10,11-epoxide-13C,d2
Chemical Name: Carbamazepine 10,11-epoxide-13C,d2
CAS Number: 1189497-48-0
Molecular Formula: C₁₄₁₃CH₁₀D₂N₂O₂
Molecular Weight: 255.27
Catalog: Research Areas Others
Create Date: 2023-04-20 16:28:17
Modify Date: 2024-01-04 20:37:39
Carbamazepine 10,11-epoxide-13C,d2 is the deuterium labeled Carbamazepine 10,11-epoxide-C13. Carbamazepine 10,11-epoxide-C13 is a 13C-labled Carbamazepine 10,11-epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1][2].

Name	Carbamazepine 10,11-epoxide-13C,d2

Description	Carbamazepine 10,11-epoxide-13C,d2 is the deuterium labeled Carbamazepine 10,11-epoxide-C13. Carbamazepine 10,11-epoxide-C13 is a 13C-labled Carbamazepine 10,11-epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1][2].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. T Tomson, et al. Single-dose kinetics and metabolism of carbamazepine-10,11-epoxide. Clin Pharmacol Ther. 1983 Jan;33(1):58-65.

Molecular Formula	C₁₄₁₃CH₁₀D₂N₂O₂
Molecular Weight	255.27