21386-86-7

21386-86-7 structure

21386-86-7 structure

Name: NSC 8751-d6
Chemical Name: NSC 8751-d6
CAS Number: 21386-86-7
Molecular Formula: C₅H₂D₆O₂
Molecular Weight: 106.15
Catalog: Research Areas Metabolic Disease
Create Date: 2023-04-27 13:40:40
Modify Date: 2024-09-10 21:56:37
NSC 8751-d6 is the deuterium labeled NSC 8751[1]. NSC 8751 is an endogenous metabolite[2].

Name	NSC 8751-d6

Description	NSC 8751-d6 is the deuterium labeled NSC 8751[1]. NSC 8751 is an endogenous metabolite[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Fausto R, et al. UV-induced isomerization of (E)-crotonic acid. Combined matrix-isolated IR and ab initio MO study[J]. Journal of the Chemical Society, Faraday Transactions, 1995, 91(21): 3755-3770. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Formula	C₅H₂D₆O₂
Molecular Weight	106.15