1955496-83-9

1955496-83-9 structure

Name: trans-trans-Muconic acid-d4
Chemical Name: trans-trans-Muconic acid-d4
CAS Number: 1955496-83-9
Molecular Formula: C₆H₂D₄O₄
Molecular Weight: 146.13
Catalog: Research Areas Metabolic Disease
Create Date: 2023-06-25 18:57:03
Modify Date: 2024-01-29 10:36:25
trans-trans-Muconic acid-d4 is the deuterium labeled trans-trans-Muconic acid[1]. trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human[2].

Name	trans-trans-Muconic acid-d4

Description	trans-trans-Muconic acid-d4 is the deuterium labeled trans-trans-Muconic acid[1]. trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bartczak A, ET AL. Evaluation of assays for the identification and quantitation of muconic acid, a benzene metabolite in human urine. J Toxicol Environ Health. 1994 Jul;42(3):245-58.

Molecular Formula	C₆H₂D₄O₄
Molecular Weight	146.13