2780364-50-1

2780364-50-1 structure

2780364-50-1 structure

Name: IL-1β-IN-1
Chemical Name: IL-1β-IN-1
CAS Number: 2780364-50-1
Molecular Formula: C₂₂H₃₄O₂
Molecular Weight: 330.50
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2023-07-24 04:37:28
Modify Date: 2024-04-07 14:42:32
IL-1β-IN-1, cannabidiol derivative, is a potent IL-1β inhibitor. IL-1β-IN-1 has anti-inflammatory and pain-resolving properties[1].

Name	IL-1β-IN-1

Description	IL-1β-IN-1, cannabidiol derivative, is a potent IL-1β inhibitor. IL-1β-IN-1 has anti-inflammatory and pain-resolving properties[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	IL-1β
In Vivo	IL-1β-IN-1 (compound 2; 10 and 25 mg/kg; i.p.; 雌性 Sabra 小鼠) 以剂量依赖性方式改善肿胀和痛感[1]。 Animal Model: female Sabra mice, 7-8 weeks old[1] Dosage: 10 and 25 mg/kg Administration: intraperitoneal injection Result: Reduced swelling and pain sensation. Reduced plasma TNFα and IL-1β.
References	[1]. Lavi Y, et, al. Novel Synthesis of C-Methylated Phytocannabinoids Bearing Anti-inflammatory Properties. J Med Chem. 2023 Apr 27;66(8):5536-5549.

Molecular Formula	C₂₂H₃₄O₂
Molecular Weight	330.50