824983-84-8

824983-84-8 structure

Name: FEN1-IN-6
Chemical Name: FEN1-IN-6
CAS Number: 824983-84-8
Molecular Formula: C₁₂H₈N₂O₅S₂
Molecular Weight: 324.33
Catalog: Signaling Pathways Immunology/Inflammation FLAP
Create Date: 2023-10-01 12:18:07
Modify Date: 2024-01-02 17:20:47
FEN1-IN-6 (compound 9) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=10 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-6 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC50 value of 23 nM[1].

Name	FEN1-IN-6

Description	FEN1-IN-6 (compound 9) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=10 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-6 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC50 value of 23 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> FLAP
References	[1]. Tumey LN, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15(2):277-81.

Molecular Formula	C₁₂H₈N₂O₅S₂
Molecular Weight	324.33