868860-35-9

868860-35-9 structure

Name: RSV L-protein-IN-3
Chemical Name: RSV L-protein-IN-3
CAS Number: 868860-35-9
Molecular Formula: C₃₁H₃₄N₄O₄
Molecular Weight: 526.63
Catalog: Signaling Pathways Anti-infection RSV
Create Date: 2023-09-20 12:15:14
Modify Date: 2024-01-10 09:43:37
RSV L-protein-IN-3 is a wild-type RSV polymerase inhibitor with an IC50 value of 10.4 μM and an EC50 value of 2.1 μM (against RSV). RSV L-protein-IN-3 has lesser cytotoxicity than the clinical agent, Ribavirin (HY-B0434)[1].

Name	RSV L-protein-IN-3

Description	RSV L-protein-IN-3 is a wild-type RSV polymerase inhibitor with an IC50 value of 10.4 μM and an EC50 value of 2.1 μM (against RSV). RSV L-protein-IN-3 has lesser cytotoxicity than the clinical agent, Ribavirin (HY-B0434)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> RSV
Target	IC50: 10.4 μM (RSV)[1]
References	[1]. Michel Liuzzi, et al. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J Virol. 2005, 79(20). [2]. Michael T. Rudd, et al. Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator. ACS Med. Chem. Lett.. 2023，14，8. [3]. Sean M Smith, et al. The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey.Neuropharmacology, 2013 Jan;64:215-23.

Molecular Formula	C₃₁H₃₄N₄O₄
Molecular Weight	526.63