Name | AZD8542 |
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Description | AZD8542 is an antagonist of Smoothened (SMO) with potential as an oncology therapeutic. |
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References | 1. Hwang RF, Moore TT, Hattersley MM, Scarpitti M, Yang B, Devereaux E, Ramachandran V, Arumugam T, Ji B, Logsdon CD, Brown JL, Godin R. Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer. Mol Cancer Res. 2012 Sep;10(9):1147-57. PubMed PMID: 22859707; PubMed Central PMCID: PMC3685283. |
Molecular Formula | C25H24N4O2 |
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Molecular Weight | 412.48 |