2221034-29-1
2221034-29-1 structure
- Name: Linrodostat mesylate
- Chemical Name: Linrodostat mesylate
- CAS Number: 2221034-29-1
- Molecular Formula: C25H28ClFN2O4S
- Molecular Weight: 507.02
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Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs).
| Name | Linrodostat mesylate |
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| Description | Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs). |
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| Molecular Formula | C25H28ClFN2O4S |
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| Molecular Weight | 507.02 |