Linrodostat mesylate

Linrodostat mesylate Structure
Linrodostat mesylate structure
Common Name Linrodostat mesylate
CAS Number 2221034-29-1 Molecular Weight 507.02
Density N/A Boiling Point N/A
Molecular Formula C25H28ClFN2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Linrodostat mesylate


Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs).

 Names

Name Linrodostat mesylate

 Linrodostat mesylate Biological Activity

Description Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs).

 Chemical & Physical Properties

Molecular Formula C25H28ClFN2O4S
Molecular Weight 507.02