897109-93-2

897109-93-2 structure

Name: F7H
Chemical Name: F7H
CAS Number: 897109-93-2
Molecular Formula: C₂₄H₁₈FN₃O₂S₂
Molecular Weight: 463.55
Catalog: Signaling Pathways Stem Cell/Wnt Wnt
Create Date: 2024-09-24 18:39:27
Modify Date: 2024-09-24 18:39:27
F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1].

Name	F7H

Description	F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt
Target	IC50: 1.25 μM (Frizzled receptor, FZD7)[1]
References	[1]. Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. .