2767011-00-5

2767011-00-5 structure

Name: BI 7446
Chemical Name: BI 7446
CAS Number: 2767011-00-5
Molecular Formula: C₂₀H₂₂FN₉O₁₀P₂S₂
Molecular Weight: 693.52
Catalog: Signaling Pathways Immunology/Inflammation STING
Create Date: 2024-01-01 00:49:17
Modify Date: 2024-01-01 00:49:17
BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research[1].

Name	BI 7446

Description	BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> STING
References	[1]. Kuttruff CA, et al. Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer. J Med Chem. 2023 Jul 27;66(14):9376-9400.

Molecular Formula	C₂₀H₂₂FN₉O₁₀P₂S₂
Molecular Weight	693.52