25269-17-4
25269-17-4 structure
- Name: ISOCEMBROL
- Chemical Name: (1R,2E,4S,7E,11E)-4-Isopropyl-1,7,11-trimethyl-2,7,11-cyclotetrad ecatrien-1-ol
- CAS Number: 25269-17-4
- Molecular Formula: C20H34O
- Molecular Weight: 290.48300
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2017-10-24 09:18:06
- Modify Date: 2024-01-02 15:06:02
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Thunbergol (Isocembrol) (Compound 17) is a potent TNF-α inhibitor with an IC50 of 7.2 μM[1].
| Name | (1R,2E,4S,7E,11E)-4-Isopropyl-1,7,11-trimethyl-2,7,11-cyclotetrad ecatrien-1-ol |
|---|---|
| Synonyms |
1H-3a,7-Methanoazulen-5(4H)-one,hexahydro-3,6,8,8-tetramethyl-,(3R,3aR,6S,7S,8aS)
CEDRALON isocedranone Cedralone 3,6,8,8-Tetramethylhexahydro-1H-3a,7-methanoazulene-5(4H)-one (3R-(3alpha,3Abeta,6alpha,7beta,8aalpha))-hexahydro-3,6,8,8-tetramethyl-1H-3A,7-methanoazulen-5(4H)-one 2-Isocedranone Cedran-9-one 9-Cedranone Isocembrol (4R) |
| Description | Thunbergol (Isocembrol) (Compound 17) is a potent TNF-α inhibitor with an IC50 of 7.2 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
TNF-α:7.2 μM (IC50) |
| References |
| Density | 0.876g/cm3 |
|---|---|
| Boiling Point | 392.69ºC at 760 mmHg |
| Molecular Formula | C20H34O |
| Molecular Weight | 290.48300 |
| Flash Point | 169.813ºC |
| Exact Mass | 290.26100 |
| PSA | 20.23000 |
| LogP | 5.81260 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.472 |
|
~%
25269-17-4 |
| Literature: Carmely, Shmuel; Groweiss, Amiram; Kashman, Yoel Journal of Organic Chemistry, 1981 , vol. 46, # 21 p. 4279 - 4284 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |