1329496-95-8

1329496-95-8 structure
1329496-95-8 structure
  • Name: Modafinil EP impurity B-d5
  • Chemical Name: Modafinil-d5 Sulfone
  • CAS Number: 1329496-95-8
  • Molecular Formula: C15H10D5NO3S
  • Molecular Weight: 294.38
  • Create Date: 2016-03-13 00:58:09
  • Modify Date: 2024-01-26 16:13:20

Name Modafinil-d5 Sulfone
Synonyms 2-[(2,3,4,5,6-pentadeuteriophenyl)-phenylmethyl]sulfonylacetamide
Description Modafinil EP impurity B-d5 是 Modafinil EP impurity B氘代物[1]。
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula C15H10D5NO3S
Molecular Weight 294.38
Exact Mass 294.10900
PSA 86.60000
LogP 3.90660