153804-05-8
153804-05-8 structure
- Name: Pratosartan
- Chemical Name: pratosartan
- CAS Number: 153804-05-8
- Molecular Formula: C25H26N6O
- Molecular Weight: 426.51400
- Catalog: Signaling Pathways GPCR/G Protein Angiotensin Receptor
- Create Date: 2017-08-17 04:23:06
- Modify Date: 2024-01-18 15:54:29
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Pratosartan is a selective angiotensin II receptor antagonist.
| Name | pratosartan |
|---|---|
| Synonyms |
Pratosartan (JAN/INN)
UNII-66VLQ6E6DL 2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6,7,8-tetrahydrocyclohepta[d]imidazol-4-one KD 3-671 KT3-671 Pratosartan |
| Description | Pratosartan is a selective angiotensin II receptor antagonist. |
|---|---|
| Related Catalog | |
| Target |
angiotensin II receptor[1] |
| In Vitro | Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT1 subtype[1]. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders[2]. |
| References |
| Density | 1.321g/cm3 |
|---|---|
| Boiling Point | 692.92ºC at 760 mmHg |
| Molecular Formula | C25H26N6O |
| Molecular Weight | 426.51400 |
| Flash Point | 372.864ºC |
| Exact Mass | 426.21700 |
| PSA | 89.35000 |
| LogP | 4.64010 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.701 |
| Storage condition | 2-8℃ |