Name | Neritaloside |
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Synonyms |
Card-20(22)-enolide, 16-(acetyloxy)-3-[(6-deoxy-3-O-methyl-β-D-galactopyranosyl)oxy]-14-hydroxy-, (3β,5β,16β)-
(3β,5β,16β)-16-Acetoxy-3-[(6-deoxy-3-O-methyl-β-D-galactopyranosyl)oxy]-14-hydroxycard-20(22)-enolide |
Description | Neritaloside could be isolated from nerium oleander. Neritaloside has central nervous system (CNS) depressant effect[1][2. |
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Related Catalog | |
In Vitro | Neritaloside (human tumor cell lines) has antitumor activity with mean IC50 value and mean IC70 value of 0.120 μM and 0.252 μM, respectively[1]. |
In Vivo | Neritaloside (25 mg/kg; i.p.; for 6 hours; mice of NMRI strain) exhibits central nervous system depressant activity in mice at a dose of 25 mg/kg[2. Animal Model: Mice of NMRI strain (18-22 g) [2 Dosage: 25 mg/kg Administration: Intraperitoneal injection; for 6 hours Result: Showed sedation in mice at 25 mg/kg dose. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 729.4±60.0 °C at 760 mmHg |
Molecular Formula | C32H48O10 |
Molecular Weight | 592.718 |
Flash Point | 229.4±26.4 °C |
Exact Mass | 592.324768 |
PSA | 140.98000 |
LogP | 3.00 |
Vapour Pressure | 0.0±5.4 mmHg at 25°C |
Index of Refraction | 1.578 |
Hazard Codes | Xi |
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