38260-01-4

38260-01-4 structure

Name: TRIETHYLENETETRAMINE DIHYDROCHLORIDE
Chemical Name: N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine,dihydrochloride
CAS Number: 38260-01-4
Molecular Formula: C₆H₂₀Cl₂N₄
Molecular Weight: 219.156
Catalog: Organic raw materials Amino compound Acyclic monoamines, polyamines and their derivatives and salts
Create Date: 2018-04-03 08:00:00
Modify Date: 2024-01-13 09:21:35

Name	N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine,dihydrochloride
Synonyms	EINECS 253-854-3 MK-0681 Triethylenetetramine dihydrochloride N,N'-bis(2-aminoéthyl)éthane-1,2-diamine dichlorhydrate Trien dihydrochloride Syprine N,N'-Bis(2-aminoethyl)-1,2-ethanediamine dihydrochloride Trientine hydrochloride MFCD00012889 n,n'-bis(2-aminoethyl)ethan-1,2-diamindihydrochlorid 1,2-Ethanediamine, N,N-bis(2-aminoethyl)-, hydrochloride (1:2) N,N'-Bis(2-aminoethyl)ethane-1,2-diamine dihydrochloride trientine dihydrochloride Triethylenetetraamine dihydrochloride

Density	0.958 g/cm3
Boiling Point	266.5ºC at 760 mmHg
Melting Point	120-125ºC (dec.)
Molecular Formula	C₆H₂₀Cl₂N₄
Molecular Weight	219.156
Flash Point	143.3ºC
Exact Mass	218.106506
PSA	76.10000
LogP	1.86940

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH8587085

CHEMICAL NAME :: 1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, dihydrochloride

CAS REGISTRY NUMBER :: 38260-01-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H18-N4.2Cl-H

MOLECULAR WEIGHT :: 219.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2285 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes Gastrointestinal - ulceration or bleeding from stomach

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: (Suppl),246,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 67500 mg/kg/90D-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration Blood - changes in spleen

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 29,185,1996 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1140 uL/kg

SEX/DURATION :: female 1-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - other effects to embryo

REFERENCE :: JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 38,545,1992

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 22800 mg/kg

SEX/DURATION :: female 1-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System

REFERENCE :: JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 39,177,1993

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	KH8587085
HS Code	2921290000

4961-40-4

~78%

38260-01-4

Literature: Jonas, Marco; Vaulont, Irene; Soi, Antonio; Schmidt, Gunther Patent: US2006/41170 A1, 2006 ; Location in patent: Page/Page column 28 ;

81904-67-8

~82%

38260-01-4

Literature: Jonas, Marco; Vaulont, Irene; Soi, Antonio; Schmidt, Gunther Patent: US2006/41170 A1, 2006 ; Location in patent: Page/Page column 21 ;

Precursor 2
4961-40-4 81904-67-8
DownStream 0

HS Code	2921290000
Summary	2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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