Name | 4-Amino-2-fluorophenol |
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Synonyms |
4-Amino-2-fluorophenol
Phenol, 4-amino-2-fluoro- 3-Fluoro-4-hydroxyaniline ZR DQ CF MFCD00671760 |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 263.3±25.0 °C at 760 mmHg |
Melting Point | 170-172°C |
Molecular Formula | C6H6FNO |
Molecular Weight | 127.116 |
Flash Point | 113.1±23.2 °C |
Exact Mass | 127.043343 |
PSA | 46.25000 |
LogP | 0.34 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.602 |
4-Amino-2-fluorophenol
Revision number: 1
SAFETY DATA SHEET Section1. BASE INFORMATION Product name:4-Amino-2-fluorophenol Revision number:1 Section2. HAZARDS IDENTIFICATION Classification of the GHS PHYSICAL HAZARDSNot classified HEALTH HAZARDS Category 4 Acute toxicity (Oral) Skin corrosion/irritationCategory 2 Category 2A Serious eye damage/eye irritation ENVIRONMENTAL HAZARDSNot classified GHS label elements Pictograms or hazard symbols Signal wordWarning Hazard statementHarmful if swallowed Causes skin irritation Causes serious eye irritation Precautionary statements [Prevention]Do not eat, drink or smoke when using this product. Wash hands thoroughly after handling. Wear protective gloves/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. [Response] Rinse mouth. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. IF ON SKIN: Gently wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. [Disposal]Dispose of contents/container through a waste management company authorized by the local government Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Component(s):4-Amino-2-fluorophenol Percent:>98.0%(GC)(T) 399-96-2 CAS Number: Synonyms:3-Fluoro-4-hydroxyaniline 4-Amino-2-fluorophenol Section3. COMPOSITION/INFORMATION ON INGREDIENTS Chemical Formula:C6H6FNO Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell. Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Ingestion: Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air- tight goggles. Section5. FIRE-FIGHTING MEASURES Dry chemical, foam, water spray, carbon dioxide. Suitable extinguishing media: Take care as it may decompose upon combustion or in high temperatures to Specific hazards: generate poisonous fume. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing Specific methods: method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak. protective equipment and Entry to non-involved personnel should be controlled around the leakage area by emergency procedures: roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated. Avoid contact with skin, eyes and clothing. Advice on safe handling: Storage Keep container tightly closed. Store in a cool and dark place. Storage conditions: Store under inert gas. Store away from incompatible materials such as oxidizing agents. Packaging material:Law is followed. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering controls:Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations. Hand protection:Protective gloves. Eye protection:Safety glasses. A face-shield, if the situation requires. Skin and body protection: Protective clothing. Protective boots, if the situation requires. 4-Amino-2-fluorophenol Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Solid Form:crystal - powder Pale yellow - Greyish yellow red Color: Odor:No data available pH: No data available Melting point/freezing point:164°C (dec.) No data available Boiling Point/Range: Flash Point:No data available Explosive limits Lower:No data available Upper:No data available Density:No data available Soluble in : Methanol Solubility: Section10. STABILITY AND REACTIVITY Stability:Stable under proper conditions. Reactivity:No special reactivity has been reported. Conditions to avoid:Air-sensitive Incompartible materials: oxidizing agents Hazardous Decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen fluoride Products: Section11. TOXICOLOGICAL INFORMATION No data available Acute Toxicity: Skin corrosion/irritation: No data available No data available Serious eye damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available No data available Reproductive toxicity: Section12. ECOLOGICAL INFORMATION Ecotoxicity: No data available Fish: Crustacea:No data available Algae:No data available Persistence / degradability: No data available BioaccumulativeNo data available potential(BCF): Mobillity in soil log Pow:No data available No data available Soil adsorption (Koc): Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations Not Listed UN-No: 4-Amino-2-fluorophenol Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. SECTION 16 - ADDITIONAL INFORMATION N/A |
Hazard Codes | Xi: Irritant; |
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Risk Phrases | R20/21/22 |
Safety Phrases | S26-S36/37/39 |
HS Code | 2907111000 |
~99% 399-96-2 |
Literature: Bristol-Myers Squibb Company Patent: US2007/78140 A1, 2007 ; Location in patent: Page/Page column 25-26 ; US 20070078140 A1 |
~% 399-96-2 |
Literature: Ishihara Sangyo Kaisha Ltd. Patent: US4861799 A1, 1989 ; |
~% 399-96-2 |
Literature: Aymes, Daniel J.; Paris, Michel R. Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 3-4 p. 175 - 178 |
~% 399-96-2 |
Literature: le Guyader,M. Bulletin de la Societe Chimique de France, 1966 , p. 1848 - 1858 |
~49% 399-96-2 |
Literature: Venugopala, K. Narayanaswamy; Prasanna, Renuka T.; Odhav, Bharti Asian Journal of Chemistry, 2013 , vol. 25, # 15 p. 8685 - 8689 |
~% 399-96-2 |
Literature: Berg; Newbery Journal of the Chemical Society, 1949 , p. 642,645 |
Precursor 6 | |
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DownStream 8 | |
HS Code | 2922299090 |
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Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |