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399-96-2

399-96-2 structure
399-96-2 structure

Name 4-Amino-2-fluorophenol
Synonyms 4-Amino-2-fluorophenol
Phenol, 4-amino-2-fluoro-
3-Fluoro-4-hydroxyaniline
ZR DQ CF
MFCD00671760
Density 1.3±0.1 g/cm3
Boiling Point 263.3±25.0 °C at 760 mmHg
Melting Point 170-172°C
Molecular Formula C6H6FNO
Molecular Weight 127.116
Flash Point 113.1±23.2 °C
Exact Mass 127.043343
PSA 46.25000
LogP 0.34
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.602
4-Amino-2-fluorophenol Revision number: 1
SAFETY DATA SHEET

Section1. BASE INFORMATION
Product name:4-Amino-2-fluorophenol

Revision number:1

Section2. HAZARDS IDENTIFICATION
Classification of the GHS
PHYSICAL HAZARDSNot classified
HEALTH HAZARDS
Category 4
Acute toxicity (Oral)
Skin corrosion/irritationCategory 2
Category 2A
Serious eye damage/eye irritation
ENVIRONMENTAL HAZARDSNot classified
GHS label elements
Pictograms or hazard symbols
Signal wordWarning
Hazard statementHarmful if swallowed
Causes skin irritation
Causes serious eye irritation
Precautionary statements
[Prevention]Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Wear protective gloves/eye protection/face protection.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
[Response]
Rinse mouth.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.
[Disposal]Dispose of contents/container through a waste management company authorized by
the local government

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Component(s):4-Amino-2-fluorophenol
Percent:>98.0%(GC)(T)
399-96-2
CAS Number:
Synonyms:3-Fluoro-4-hydroxyaniline
4-Amino-2-fluorophenol

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Formula:C6H6FNO

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Ingestion:
Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Dry chemical, foam, water spray, carbon dioxide.
Suitable extinguishing
media:
Take care as it may decompose upon combustion or in high temperatures to
Specific hazards:
generate poisonous fume.
Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
Specific methods:
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Handling
Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Avoid contact with skin, eyes and clothing.
Advice on safe handling:
Storage
Keep container tightly closed. Store in a cool and dark place.
Storage conditions:
Store under inert gas.
Store away from incompatible materials such as oxidizing agents.
Packaging material:Law is followed.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls:Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection:Protective gloves.
Eye protection:Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.
4-Amino-2-fluorophenol

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Form:crystal - powder
Pale yellow - Greyish yellow red
Color:
Odor:No data available
pH: No data available
Melting point/freezing point:164°C (dec.)
No data available
Boiling Point/Range:
Flash Point:No data available
Explosive limits
Lower:No data available
Upper:No data available
Density:No data available
Soluble in : Methanol
Solubility:

Section10. STABILITY AND REACTIVITY
Stability:Stable under proper conditions.
Reactivity:No special reactivity has been reported.
Conditions to avoid:Air-sensitive
Incompartible materials: oxidizing agents
Hazardous Decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen fluoride
Products:

Section11. TOXICOLOGICAL INFORMATION
No data available
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC =No data available
NTP =No data available
No data available
Reproductive toxicity:

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
No data available
Fish:
Crustacea:No data available
Algae:No data available
Persistence / degradability: No data available
BioaccumulativeNo data available
potential(BCF):
Mobillity in soil
log Pow:No data available
No data available
Soil adsorption (Koc):
Henry's LawNo data available
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:Does not correspond to the classification standard of the United Nations
Not Listed
UN-No:
4-Amino-2-fluorophenol

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26,
2002): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were
prescribed.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi: Irritant;
Risk Phrases R20/21/22
Safety Phrases S26-S36/37/39
HS Code 2907111000

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399-96-2

Literature: Bristol-Myers Squibb Company Patent: US2007/78140 A1, 2007 ; Location in patent: Page/Page column 25-26 ; US 20070078140 A1

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Literature: Ishihara Sangyo Kaisha Ltd. Patent: US4861799 A1, 1989 ;

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Literature: Aymes, Daniel J.; Paris, Michel R. Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 3-4 p. 175 - 178

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399-96-2

Literature: le Guyader,M. Bulletin de la Societe Chimique de France, 1966 , p. 1848 - 1858

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399-96-2 structure

399-96-2

Literature: Venugopala, K. Narayanaswamy; Prasanna, Renuka T.; Odhav, Bharti Asian Journal of Chemistry, 2013 , vol. 25, # 15 p. 8685 - 8689

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399-96-2 structure

399-96-2

Literature: Berg; Newbery Journal of the Chemical Society, 1949 , p. 642,645
HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%