203784-63-8

203784-63-8 structure
203784-63-8 structure
  • Name: DL-Valine-d8
  • Chemical Name: 2-amino-2,3,4,4,4-pentadeuterio-3-(trideuteriomethyl)butanoic acid
  • CAS Number: 203784-63-8
  • Molecular Formula: C5H3D8NO2
  • Molecular Weight: 125.20
  • Create Date: 2018-09-27 15:04:48
  • Modify Date: 2024-01-11 18:51:41
  • DL-Valine-d8 is the deuterium labeled DL-Valine[1].

Name 2-amino-2,3,4,4,4-pentadeuterio-3-(trideuteriomethyl)butanoic acid
Synonyms DL-Valine-2,3,4,4,4,5,5,5-d8
MFCD00144194
DL-Valine-d8
Description DL-Valine-d8 is the deuterium labeled DL-Valine[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Density 1.136g/cm3
Boiling Point 213.6ºC at 760 mmHg
Melting Point 295ºC (subl.)(lit.)
Molecular Formula C5H3D8NO2
Molecular Weight 125.20
Flash Point 83ºC
Exact Mass 125.12900
PSA 63.32000
LogP 0.75460
Vapour Pressure 0.0633mmHg at 25°C
Index of Refraction 1.461
Storage condition 2-8°C
RIDADR NONH for all modes of transport