CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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QV0100000
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CHEMICAL NAME :
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Nitric acid, methyl ester
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CAS REGISTRY NUMBER :
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598-58-3
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BEILSTEIN REFERENCE NO. :
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1699872
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C-H3-N-O3
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MOLECULAR WEIGHT :
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77.05
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WISWESSER LINE NOTATION :
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WNO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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344 mg/kg
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TOXIC EFFECTS :
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Blood - methemoglobinemia-carboxyhemoglobin
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REFERENCE :
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AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: TR-77-25,1977
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1275 ppm/4H
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TOXIC EFFECTS :
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Blood - methemoglobinemia-carboxyhemoglobin
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REFERENCE :
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AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: TR-77-25,1977
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1820 mg/kg
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TOXIC EFFECTS :
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Blood - methemoglobinemia-carboxyhemoglobin
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REFERENCE :
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AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: TR-77-25,1977
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TYPE OF TEST :
-
LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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5942 ppm/4H
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TOXIC EFFECTS :
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Blood - methemoglobinemia-carboxyhemoglobin
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REFERENCE :
-
AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: TR-77-25,1977
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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548 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes Liver - other changes Blood - methemoglobinemia-carboxyhemoglobin
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REFERENCE :
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AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: TR-77-25,1977
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