Name | 2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid |
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Synonyms | hms1431a19 |
Description | Jedi2 is a Piezo1 channel activator, but no specific Piezo2 activators. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770 μM[1]. |
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Related Catalog | |
In Vitro | Jedi2 evokes Piezo1-mediated Ca2+ influx. Jedi2 (200 μM) specifically elicits dose-dependent responses in mPiezo1-transfected cells, but not in mPiezo2- or vector-transfected cells [1]. Jedi2 (1 mM) causes an increase in Ca2+ in mCherry-positive HEK293T cells transfected with the mPiezo1-mCherry construct, which also responded to Yoda1 (30 μM) [1]. |
References |
Molecular Formula | C10H8O3S |
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Molecular Weight | 208.23400 |
Exact Mass | 208.01900 |
PSA | 78.68000 |
LogP | 3.01470 |
Hazard Codes | Xn |
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