169211-45-4

169211-45-4 structure

Name: DiSBAC10
Chemical Name: 1,3-didecyl-5-[3-(1,3-didecylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene]dihydro-2-thioxo-4,6-(1h,5h)-pyrimidinedione
CAS Number: 169211-45-4
Molecular Formula: C₅₁H₈₈N₄O₄S₂
Molecular Weight: 885.40
Catalog: Research Areas Others
Create Date: 2016-10-06 10:30:33
Modify Date: 2024-01-21 10:42:44
DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.

Name	1,3-didecyl-5-[3-(1,3-didecylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene]dihydro-2-thioxo-4,6-(1h,5h)-pyrimidinedione
Synonyms	disbac10 4,6(1H,5H)-Pyrimidinedione, 5,5'-[(1E)-1-propen-1-yl-3-ylidene]bis[1,3-didecyldihydro-2-thioxo- 5,5'-[(1E)-1-Propen-1-yl-3-ylidene]bis(1,3-didecyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione)

Description	DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
Related Catalog	Research Areas >> Others