DiSBAC10

Modify Date: 2024-01-21 10:42:44

DiSBAC10 Structure
DiSBAC10 structure
Common Name DiSBAC10
CAS Number 169211-45-4 Molecular Weight 885.40
Density 1.1±0.1 g/cm3 Boiling Point 844.6±75.0 °C at 760 mmHg
Molecular Formula C51H88N4O4S2 Melting Point N/A
MSDS N/A Flash Point 464.6±37.1 °C

 Use of DiSBAC10


DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.

 Names

Name 1,3-didecyl-5-[3-(1,3-didecylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene]dihydro-2-thioxo-4,6-(1h,5h)-pyrimidinedione
Synonym More Synonyms

 DiSBAC10 Biological Activity

Description DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
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 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 844.6±75.0 °C at 760 mmHg
Molecular Formula C51H88N4O4S2
Molecular Weight 885.40
Flash Point 464.6±37.1 °C
Exact Mass 884.624695
PSA 145.42000
LogP 16.84
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.551

 Synonyms

disbac10
4,6(1H,5H)-Pyrimidinedione, 5,5'-[(1E)-1-propen-1-yl-3-ylidene]bis[1,3-didecyldihydro-2-thioxo-
5,5'-[(1E)-1-Propen-1-yl-3-ylidene]bis(1,3-didecyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione)
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