146478-73-1

146478-73-1 structure

Name: FR901465
Chemical Name: fr901465
CAS Number: 146478-73-1
Molecular Formula: C₂₇H₄₁NO₉
Molecular Weight: 523.61600
Catalog: Research Areas Cancer
Create Date: 2017-11-01 10:59:15
Modify Date: 2023-01-18 16:38:08
FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1].

Name	fr901465
Synonyms	WB 2663C [(Z,2S)-5-[[(2R,3R,5S,6S)-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3S,4R,5R,7R,8R)-4,5,8-trihydroxy-5-methyl-1,6-dioxaspiro[2.5]octan-7-yl]penta-2,4-dienyl]oxan-3-yl]amino]-5-oxopent-3-en-2-yl] acetate

Description	FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	FR901465 prolongs the life of mice bearing murine ascitic tumor P388 leukemia (T/C values 127% for FR901465 in mice bearing murine ascitic tumors[1].
References	[1]. H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. [2]. H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. [3]. Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT