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  • China
  • Product Name: CE6
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19660-77-6

19660-77-6 structure
19660-77-6 structure
  • Name: Chlorine a6
  • Chemical Name: chlorin e6
  • CAS Number: 19660-77-6
  • Molecular Formula: C34H36N4O6
  • Molecular Weight: 596.673
  • Catalog: Research Areas Cancer
  • Create Date: 2018-04-16 08:00:00
  • Modify Date: 2024-01-03 13:36:57
  • Chlorin e6 is a photosensitizer. Chlorin e6 has significantly high photosensitizing activity when present in insulin-containing conjugates and thus able to be internalized by receptor-expressing cells. Chlorin E6 effects viability and mitochondrial activity of Leishmania major and Leishmania braziliensis promastigotes[1][2].

Name chlorin e6
Synonyms (17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-2-carboxylic acid
PHYTOCHLORIN
EINECS 243-209-4
(17S,18S)-18-(2-Carboxyethyl)-20-(carboxymethyl)-7-ethyl-3,8,13,17-tetramethyl-12-vinyl-17,18-dihydro-2-porphyrincarboxylic acid
(17S,18S)-18-(2-Carboxyethyl)-20-(carboxymethyl)-7-ethyl-3,8,13,17-tetramethyl-12-vinyl-17,18-dihydroporphyrin-2-carboxylic acid
Phytochlorin e6
Chlorine e6
21H,22H-Porphine-13-propanoic acid, 17-carboxy-15-(carboxymethyl)-7-ethenyl-2-ethyl-12,13-dihydro-3,8,12,18-tetramethyl-, (12S,13S)-
Phytochlorine e
Chlorine a6
Description Chlorin e6 is a photosensitizer. Chlorin e6 has significantly high photosensitizing activity when present in insulin-containing conjugates and thus able to be internalized by receptor-expressing cells. Chlorin E6 effects viability and mitochondrial activity of Leishmania major and Leishmania braziliensis promastigotes[1][2].
Related Catalog
References

[1]. Pinto JG, et al. Chlorin E6 phototoxicity in L. major and L. braziliensis promastigotes-In vitro study. Photodiagnosis Photodyn Ther. 2016 Sep;15:19-24.

[2]. Akhlynina TV, et al. Nuclear targeting of chlorin e6 enhances its photosensitizing activity. J Biol Chem. 1997 Aug 15;272(33):20328-31.

Density 1.3±0.1 g/cm3
Boiling Point 1048.3±65.0 °C at 760 mmHg
Molecular Formula C34H36N4O6
Molecular Weight 596.673
Flash Point 587.8±34.3 °C
Exact Mass 596.263489
PSA 168.20000
LogP 6.73
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.643
Storage condition -20°C