1041-90-3

1041-90-3 structure

1041-90-3 structure

Name: nalorphine hydrobromide
Chemical Name: (4R,4aR,7S,7aR,12bS)-9-methoxy-3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrobromide
CAS Number: 1041-90-3
Molecular Formula: C₁₉H₂₂BrNO₃
Molecular Weight: 392.28700
Catalog: API Special medicine Antidote
Create Date: 2018-02-20 08:00:00
Modify Date: 2024-01-11 12:29:09

Name	(4R,4aR,7S,7aR,12bS)-9-methoxy-3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrobromide
Synonyms	N-Allylnormorphine hydrobromide Nalorphine hydrobromide C19H21NO3.HBr Nalorphine bromide EINECS 213-868-2

Boiling Point	493.6ºC at 760mmHg
Melting Point	208ºC
Molecular Formula	C₁₉H₂₂BrNO₃
Molecular Weight	392.28700
Flash Point	252.3ºC
Exact Mass	391.07800
PSA	52.93000
LogP	2.65030
Vapour Pressure	1.46E-10mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QC7705000

CHEMICAL NAME :: Morphinan-3,6-alpha-diol, 17-allyl-7,8-didehydro-4,5-alpha-epoxy-, hydrobromide

CAS REGISTRY NUMBER :: 1041-90-3

LAST UPDATED :: 199512

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H21-N-O3.Br-H

MOLECULAR WEIGHT :: 392.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 260 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 51,199,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 921 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,668,1969