5959-80-8

5959-80-8 structure

Name: (3-methylphenyl)-[8-[3-(trifluoromethyl)phenyl]sulfonyl-1-thia-4,8-diazaspiro[4.5]decan-4-yl]methanone
Chemical Name: (3-methylphenyl)-[8-[3-(trifluoromethyl)phenyl]sulfonyl-1-thia-4,8-diazaspiro[4.5]decan-4-yl]methanone
CAS Number: 5959-80-8
Molecular Formula: C₂₂H₂₃F₃N₂O₃S₂
Molecular Weight: 484.55500
Create Date: 2017-08-02 19:16:02
Modify Date: 2024-01-10 16:50:16

Name	(3-methylphenyl)-[8-[3-(trifluoromethyl)phenyl]sulfonyl-1-thia-4,8-diazaspiro[4.5]decan-4-yl]methanone
Synonyms	2-[2-(1H-imidazol-4-yl)-ethyl]-isoindole-1,3-dione (3-methylphenyl)-[8-[3-(trifluoromethyl)phenyl]sulfonyl-4-thia-1,8-diazaspiro[4.5]decan-1-yl]methanone N-phthaloyl histamine Na-phthaloylhistamine N-[2-(1(3)H-imidazol-4-yl)-ethyl]-phthalimide 4(5)-(2-phthalimidoethyl)imidazole

Density	1.45g/cm3
Boiling Point	634.4ºC at 760mmHg
Molecular Formula	C₂₂H₂₃F₃N₂O₃S₂
Molecular Weight	484.55500
Flash Point	337.5ºC
Exact Mass	484.11000
PSA	91.37000
LogP	5.34040
Index of Refraction	1.631

22509-74-6

56-92-8

~10%

5959-80-8

Literature: Schering Corporation; Pharmacopeia Drug Discovery, Inc. Patent: EP1140909 B1, 2005 ; Location in patent: Page/Page column 73 ;

85-44-9

51-45-6

~87%

5959-80-8

Literature: Kamaraj, Kaliappan; Kim, Eunsuk; Galliker, Benedikt; Zakharov, Lev N.; Rheingold, Arnold L.; Zuberbuehler, Andreas D.; Karlin, Kenneth D. Journal of the American Chemical Society, 2003 , vol. 125, # 20 p. 6028 - 6029

22509-74-6

51-45-6

5959-80-8

Literature: NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2005/21519 A2, 2005 ; Location in patent: Page/Page column 36 ; WO 2005/021519 A2

14997-56-9

~20%

136918-14-4

5959-80-8

Literature: Griesbeck, Axel G.; Neudoerfl, Joerg; Kiff, Alan De Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 518 - 524

14997-56-9

~29%

5959-80-8

Literature: Sato, Yasuhiko; Nakai, Hideo; Mizoguchi, Tomishige; Kawanishi, Masazumi; Hatanaka, Yasumaru; Kanaoka, Yuichi Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1263 - 1270

22509-74-6

71-00-1

136918-14-4

5959-80-8

Literature: Griesbeck, Axel G.; Neudoerfl, Joerg; Kiff, Alan De Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 518 - 524

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4