Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Shionone
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: Shionone
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Shionone
Price: ￥1178.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: shionone
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

10376-48-4

10376-48-4 structure

10376-48-4 structure

Name: Shionone
Chemical Name: shionone
CAS Number: 10376-48-4
Molecular Formula: C₃₀H₅₀O
Molecular Weight: 426.717
Catalog: Biochemical Plant extracts
Create Date: 2018-05-04 08:00:00
Modify Date: 2024-01-03 00:10:42
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities[1][2]. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure[1].

Name	shionone
Synonyms	(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-Hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one SHIONONE 21-Shionen-3-one (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-Hexamethyl-8-(4-methyl-3-penten-1-yl)hexadecahydro-2(1H)-chrysenone 2(1H)-Chrysenone, hexadecahydro-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methyl-3-penten-1-yl)-, (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)- 3b,5a,8,17ab-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homoandrostan-17-one 18,19-Seco-D:A-friedolup-19-en-3-one D:A-Friedo-18,19-secolup-19-en-3-one

Description	Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities[1][2]. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema[1]. Animal Model: ICR male mice[1] Dosage: 80 mg/kg Administration: Orally administration; 3 days; once daily Result: Reduced the ear edema for 11.3% by use shionone.
References	[1]. Sawai S, et al. Molecular characterization of an oxidosqualene cyclase that yields shionone, a unique tetracyclic triterpene ketone of Aster tataricus.FEBS Lett. 2011 Apr 6;585(7):1031-6. [2]. Yu P, et al. Expectorant, antitussive, anti-inflammatory activities and compositional analysis of Aster tataricus.J Ethnopharmacol. 2015 Apr 22;164:328-33.

Density	0.9±0.1 g/cm3
Boiling Point	485.6±14.0 °C at 760 mmHg
Melting Point	161-162°
Molecular Formula	C₃₀H₅₀O
Molecular Weight	426.717
Flash Point	200.5±15.1 °C
Exact Mass	426.386169
PSA	17.07000
LogP	11.00
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.498

Safety Phrases	24/25
HS Code	29143990