Name | 5-Chloroethyl-6-Chloro-1,3-Dihydro-2H-Indole-2-One |
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Synonyms |
2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-
T56 BMV DHJ G2G HG MFCD03411598 6-Chloro-5-(2-chloroethyl)-2-indolinone 6-Chloro-5-(2-chloroethyl)oxindole 6-Chloro-5-(2-chloroethyl)indolin-2-one 5-Chloroethyl-6-chloro-1,3-dihydro-2H-indole-2-one 6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one EINECS 421-320-0 |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 393.8±42.0 °C at 760 mmHg |
Melting Point | 218-221ºC |
Molecular Formula | C10H9Cl2NO |
Molecular Weight | 230.091 |
Flash Point | 192.0±27.9 °C |
Exact Mass | 229.006119 |
PSA | 29.10000 |
LogP | 2.82 |
Vapour Pressure | 0.0±0.9 mmHg at 25°C |
Index of Refraction | 1.592 |
Storage condition | Refrigerator |
6-Chloro-5-(2-chloroethyl)oxindole
SAFETY DATA SHEET Section1. IDENTIFICATION Product name:6-Chloro-5-(2-chloroethyl)oxindole Section2. HAZARDS IDENTIFICATION GHS classification
PHYSICAL HAZARDSNot classified
Not classified HEALTH HAZARDS ENVIRONMENTAL HAZARDS Category 1 Acute aquatic hazard Long-term aquatic hazardCategory 1 GHS label elements, including precautionary statements Pictograms or hazard symbols Signal wordWarning Hazard statements Very toxic to aquatic life Very toxic to aquatic life with long lasting effects Precautionary statements: [Prevention]Avoid release to the environment. Collect spillage. [Response] [Disposal]Dispose of contents/container through a waste management company authorized by the local government. Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Components:6-Chloro-5-(2-chloroethyl)oxindole Percent:>98.0%(GC) CAS Number:118289-55-7 Synonyms:6-Chloro-5-(2-chloroethyl)-2-indolinone Chemical Formula:C10H9Cl2NO Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell. Skin contact:Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. If skin irritation or rash occurs: Get medical advice/attention. 6-Chloro-5-(2-chloroethyl)oxindole Section4. FIRST AID MEASURES Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth. Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air- tight goggles. Section5. FIRE-FIGHTING MEASURES Dry chemical, foam, water spray, carbon dioxide. Suitable extinguishing media: Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to from the chemical:generate poisonous fume. Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak. protective equipment and Entry to non-involved personnel should be controlled around the leakage area by emergency procedures: roping off, etc. Environmental precautions: Be careful not to let it flow into rivers, etc., since adverse effects on the environment are concerned. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a refrigerator. Store away from incompatible materials such as oxidizing agents. Heat-sensitive Packaging material:Comply with laws. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering controls:Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations. Hand protection:Protective gloves. Safety glasses. A face-shield, if the situation requires. Eye protection: Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Solid Crystal- Powder Form: Colour:Very pale yellow - Pale reddish yellow No data available Odour: 6-Chloro-5-(2-chloroethyl)oxindole Section9. PHYSICAL AND CHEMICAL PROPERTIES pH: No data available Melting point/freezing point:225°C Boiling point/range:No data available Flash point:No data available Flammability or explosive limits: Lower:No data available Upper:No data available Relative density:No data available Solubility(ies): [Water]No data available [Other solvents] Soluble:Dimethylformamide(DMF) Section10. STABILITY AND REACTIVITY Chemical stability:Stable under proper conditions. Possibility of hazardous No special reactivity has been reported. reactions: Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride products: Section11. TOXICOLOGICAL INFORMATION Acute Toxicity:No data available Skin corrosion/irritation: No data available Serious eyeNo data available damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available Reproductive toxicity:No data available Section12. ECOLOGICAL INFORMATION Ecotoxicity: Fish:No data available Crustacea:No data available No data available Algae: Persistence / degradability: No data available No data available Bioaccumulative potential(BCF): Mobility in soil Log Pow:No data available Soil adsorption (Koc):No data available Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:9: Miscellaneous dangerous goods. UN-No:3077 Proper shipping name:Environmentally hazardous substance, solid, n.o.s. 6-Chloro-5-(2-chloroethyl)oxindole Section14. TRANSPORT INFORMATION Packing group:III Marine pollutantY Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. SECTION 16 - ADDITIONAL INFORMATION N/A |
Hazard Codes | N: Dangerous for the environment; |
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Risk Phrases | R50/53 |
Safety Phrases | 60-61 |
HS Code | 2933790090 |
~% 118289-55-7 |
Literature: Journal of Medicinal Chemistry, , vol. 39, # 1 p. 143 - 148 |
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Literature: US2007/117810 A1, ; Page/Page column 3 ; |
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Literature: US2006/89502 A1, ; Page/Page column 7 ; |
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Literature: Journal of Medicinal Chemistry, , vol. 39, # 1 p. 143 - 148 |
~% 118289-55-7 |
Literature: Organic Process Research and Development, , vol. 7, # 3 p. 309 - 312 |
~% 118289-55-7 |
Literature: Organic Process Research and Development, , vol. 7, # 3 p. 309 - 312 |
~% 118289-55-7 |
Literature: WO2012/20424 A1, ; |
~% 118289-55-7 |
Literature: WO2012/20424 A1, ; |
~% 118289-55-7 |
Literature: Organic Process Research and Development, , vol. 12, # 6 p. 1142 - 1145 |
Precursor 7 | |
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DownStream 1 | |
HS Code | 2933790090 |
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Summary | 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0% |