Nanjing Peptide Biotech Ltd
China
Product Name: Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

310427-94-2

310427-94-2 structure

Name: Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Chemical Name: Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg
CAS Number: 310427-94-2
Molecular Formula: C₉₁H₁₂₉N₂₅O₂₅S
Molecular Weight: 2005.22
Catalog: Signaling Pathways Neuronal Signaling Beta-secretase
Create Date: 2019-01-13 20:48:18
Modify Date: 2024-02-24 19:06:05
RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1].

Name	Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg
Synonyms	arg-glu(edans)-glu-val-asn-leu-asp-ala-glu-phe-lys(dabcyl)-arg h-arg-glu(edans)-glu-val-asn-leu-asp-ala-glu-phe-lys(dabcyl)-arg-oh arg-glu(edans)-[asn670,leu671]-amyloid b/a4 protein precursor 770 fragment 669-674-(dabcyl)lys-arg arg-glu(edans)-(asn670,leu671)-app770 (668-675)-lys(dabcyl)-arg

Description	RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
References	[1]. Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7.

Safety Phrases	22-24/25
WGK Germany	3