Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxo-
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1405-90-9

1405-90-9 structure

1405-90-9 structure

Name: Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxo-
Chemical Name: (4E,6E,8E,10E,12E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,32,33,35,37-heptahydroxy-18,20,21-trimethyl-23,29-dioxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid
CAS Number: 1405-90-9
Molecular Formula: C₄₇H₇₁NO₁₇
Molecular Weight: 922.06300
Create Date: 2016-06-19 08:15:41
Modify Date: 2023-01-17 19:13:25

Name	(4E,6E,8E,10E,12E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,32,33,35,37-heptahydroxy-18,20,21-trimethyl-23,29-dioxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid
Synonyms	EINECS 215-788-3 CANDIDIN 8,9-Dideoxy-10-hydroxy-7-oxoamphotericin B Amphotericin B,8,9-dideoxy-10-hydroxy-7-oxo

Molecular Formula	C₄₇H₇₁NO₁₇
Molecular Weight	922.06300
Exact Mass	921.47200
PSA	316.45000
LogP	1.62020
Index of Refraction	1.601

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EX4375000

CHEMICAL NAME :: Candidin

CAS REGISTRY NUMBER :: 1405-90-9

LAST UPDATED :: 199210

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C46-H71-N-O17

MOLECULAR WEIGHT :: 910.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,288,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,263,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,263,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,263,1989