Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Benzcyclane
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: bencyclane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2179-37-5

2179-37-5 structure

2179-37-5 structure

Name: Benzcyclane
Chemical Name: 3-(1-benzylcycloheptyl)oxy-N,N-dimethylpropan-1-amine
CAS Number: 2179-37-5
Molecular Formula: C₁₉H₃₁NO
Molecular Weight: 289.45600
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-10-03 15:11:34
Modify Date: 2024-01-06 18:19:04
Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and a vasodilator effective in a variety of peripheral circulation disorders.

Name	3-(1-benzylcycloheptyl)oxy-N,N-dimethylpropan-1-amine
Synonyms	Benzcyclan EINECS 218-547-0 BENCYCLANE Benzcyclane

Description	Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and a vasodilator effective in a variety of peripheral circulation disorders.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease
In Vivo	Benzcyclane, although capable of aggregating platelets by itself at very high concentrations, shows a striking inhibitory effect, over a wide range of concentrations, both on platelet aggregation induced by ADP, epinephrine or collagen and on platelet adhesiveness to glass or collagen. Clot retraction is also clearly inhibited[1]. Benzcyclane induces use-dependent inhibition of Na channels in muscle, similarly as do class 1 antiarrhytnmic drugs. Inhibition was observed with both normal and cevadine-modified Na channels[2].
References	[1]. Ponari O, et al. In vitro effects of bencyclan on coagulation, fibrinolysis and platelet function. Arzneimittelforschung. 1976;26(8):1532-8. [2]. Nánási PP, et al. Effects of bencyclane on normal and cevadine-modified Na channels in frog skeletal muscle. Gen Physiol Biophys. 1989 Oct;8(5):447-58.

Density	0.97g/cm3
Boiling Point	384.2ºC at 760mmHg
Molecular Formula	C₁₉H₃₁NO
Molecular Weight	289.45600
Flash Point	113.2ºC
Exact Mass	289.24100
PSA	12.47000
LogP	4.29040
Vapour Pressure	4.17E-06mmHg at 25°C
Index of Refraction	1.52
Storage condition	2-8℃

HS Code	2922199090

4006-73-9 structure

4006-73-9

109-54-6 structure

109-54-6

~%

2179-37-5 structure

2179-37-5

Literature: Pallos; Budai; Zolyomi Arzneimittel-Forschung, 1972 , vol. 22, # 9 p. 1502 - 1505

Precursor 2
4006-73-9 109-54-6
DownStream 1
22671-53-0

HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%