66474-53-1
66474-53-1 structure
- Name: NSC 311068
- Chemical Name: 2-(2,4-dinitrophenyl)sulfanylpyrimidine
- CAS Number: 66474-53-1
- Molecular Formula: C10H6N4O4S
- Molecular Weight: 278.24400
- Create Date: 2017-02-21 03:04:33
- Modify Date: 2024-01-14 11:25:02
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NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
| Name | 2-(2,4-dinitrophenyl)sulfanylpyrimidine |
|---|---|
| Synonyms |
Jcc 216
<2,4-Dinitrophenyl>-pyrimidyl-thioaether 1-(pyrimidin-2-ylthio)-2,4-dinitrobenzene 2,4-Dinitropyrimidinyl-2-thiophenol Pyrimidine,2-((2,4-dinitrophenyl)thio) 1-(2'-thiopyrimidine)-2,4-dinitrobenzene HMS2812A16 |
| Density | 1.6g/cm3 |
|---|---|
| Boiling Point | 506.5ºC at 760 mmHg |
| Molecular Formula | C10H6N4O4S |
| Molecular Weight | 278.24400 |
| Flash Point | 260.1ºC |
| Exact Mass | 278.01100 |
| PSA | 142.72000 |
| LogP | 3.49060 |
| Index of Refraction | 1.7 |
|
~77%
66474-53-1 |
| Literature: El-Bardan, Ali A.; Hamed, Ezzat A.; Aboul-Ela, Salah L.; Moussa, Adel M. Journal of the Indian Chemical Society, 1997 , vol. 74, # 7 p. 575 - 578 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |