Top Suppliers:I want be here


18662-53-8

18662-53-8 structure
18662-53-8 structure

Name trisodium,2-[bis(carboxylatomethyl)amino]acetate,hydrate
Synonyms EINECS 225-768-6
NITRILOTRIACETIC ACID TRISODIUM MONOHYDRATE
Nitrilotriacetic acid
MFCD00150789
Sodium nitrilotriacetate tribasic monohydrate
Trisodium nitrilotriacetate monohydrate
Nitrilotriacetic acid trisodium salt monohydrate
NTA trisodium salt dihydrate
Nitriloacetic acid trisodium salt monohydrate
NTA 3Na Monohydrate
Triglycollamic Acid Trisodium Salt Monohydrate
NTA sodium hydrate
Density 1,27 g/cm3
Boiling Point 498.2ºC at 760mmHg
Melting Point >300 °C(lit.)
Molecular Formula C6H8NNa3O7
Molecular Weight 275.10000
Flash Point 255.1ºC
Exact Mass 274.99900
PSA 132.86000
Vapour Pressure 2.78E-11mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ1070000
CHEMICAL NAME :
Acetic acid, nitrilotri-, trisodium salt, monohydrate
CAS REGISTRY NUMBER :
18662-53-8
LAST UPDATED :
199510
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C6-H6-N-O6.3Na.H2-O
MOLECULAR WEIGHT :
311.16
WISWESSER LINE NOTATION :
QV1N1VQ1VQ &-NA- 3 &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
44434 ug/kg/4W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - changes in calcium
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60988 mg/kg/7W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
830 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
315 gm/kg/75W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
876 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
900 ug/kg
SEX/DURATION :
female 9-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - urogenital system

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
11 umol/L
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 25,137,1985 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,181,1990 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,181,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9062 No. of Facilities: 1167 (estimated) No. of Industries: 25 No. of Occupations: 28 No. of Employees: 21592 (estimated) No. of Female Employees: 9232 (estimated)
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H302-H319-H351
Precautionary Statements P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful;
Risk Phrases R22;R40
Safety Phrases S36/37
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS AJ1070000
HS Code 2921199090
HS Code 2921199090
Summary 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%