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51314-51-3

51314-51-3 structure
51314-51-3 structure
  • Name: 1H-Benzimidazol-2-amine,N-butyl-
  • Chemical Name: butyl(1,3-dihydrobenzimidazol-2-ylidene)azanium
  • CAS Number: 51314-51-3
  • Molecular Formula: C11H15N3
  • Molecular Weight: 189.26
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-12-29 14:38:57
  • Modify Date: 2024-01-17 14:54:12
  • M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1].

Name butyl(1,3-dihydrobenzimidazol-2-ylidene)azanium
Synonyms 2-N-butylamino-1H-benzimidazole
2-n-Butylaminobenzimidazol
N-Butyl-1H-Benzimidazol-2-Amine
Description M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1].
Related Catalog
References

[1]. Ai-Jun Ding, et al. Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. Mol Cell Biochem. 2017 Feb;426(1-2):101-109.  

Density 1.153g/cm3
Boiling Point 344.8ºC at 760 mmHg
Molecular Formula C11H15N3
Molecular Weight 189.26
Flash Point 162.3ºC
Exact Mass 189.12700
PSA 40.71000
LogP 2.84790
Index of Refraction 1.653
HS Code 2933990090

~57%

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51314-51-3

Literature: Linciano, Pasquale; Pizzetti, Marianna; Porcheddu, Andrea; Taddei, Maurizio Synlett, 2013 , vol. 24, # 17 p. 2249 - 2254

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Literature: Zhu, Jinmei; Wu, Chun-Feng; Li, Xiaobing; Wu, Gui-Sheng; Xie, Shan; Hu, Qian-Nan; Deng, Zixin; Zhu, Michael X.; Luo, Huai-Rong; Hong, Xuechuan Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 14 p. 4218 - 4224

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Literature: Li, Feng; Kang, Qikai; Shan, Haixia; Chen, Lin; Xie, Jianjiang European Journal of Organic Chemistry, 2012 , # 26 p. 5085 - 5092

~71%

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Literature: Zhu, Tong-Hao; Wang, Shun-Yi; Wang, Gao-Nan; Ji, Shun-Jun Chemistry - A European Journal, 2013 , vol. 19, # 19 p. 5850 - 5853

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Literature: Barrett, Ian C.; Kerr, Michael A. Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2439 - 2442

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51314-51-3

Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348

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51314-51-3 structure

51314-51-3

Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348

~%

51314-51-3 structure

51314-51-3

Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348

~%

51314-51-3 structure

51314-51-3

Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%