409081-12-5

409081-12-5 structure

Name: 4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride
Chemical Name: methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate,hydrochloride
CAS Number: 409081-12-5
Molecular Formula: C₂₅H₂₇ClN₄O₄
Molecular Weight: 482.96
Catalog: Signaling Pathways Metabolic Enzyme/Protease Factor Xa
Create Date: 2016-05-29 22:08:49
Modify Date: 2024-02-05 15:24:10
Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (Ki=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa[1].

Name	methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate,hydrochloride
Synonyms	Methyl (2R,3R)-2-(3-amidinobenzyl)-3-((4-(1-oxido-4-pyridinyl)benzoyl)amino)butanoate hydrochloride 4-(4-((2R,3R)-3-(3-carbamimidoylbenzyl)-4-methoxy-4-oxobutan-2-ylcarbamoyl)phenyl)pyridine 1-oxide hydrochloride Otamixaban hydrochloride [WHO-DD] Otamixaban hydrochloride UNII-WL9J31M2HI

Description	Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (Ki=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa
Target	IC50: Factor Xa[1]
References	[1]. Eikelboom JW, Weitz JI.Otamixaban in acute coronary syndromes.Lancet. 2009 Sep 5;374(9692):762-4. Epub 2009 Aug 28.