62948-75-8

62948-75-8 structure
62948-75-8 structure
  • Name: Uric acid-15N2
  • Chemical Name: 7,9-dihydro-3H-purine-2,6,8-trione
  • CAS Number: 62948-75-8
  • Molecular Formula: C5H4N4O3
  • Molecular Weight: 170.09700
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-09-24 09:00:23
  • Modify Date: 2024-01-05 14:19:20
  • Uric acid-15N2 is the 15N labeled Uric acid[1]. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[2][3].

Name 7,9-dihydro-3H-purine-2,6,8-trione
Synonyms Uric acid-1,3-15N2
MFCD00145511
Description Uric acid-15N2 is the 15N labeled Uric acid[1]. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845.  

[3]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 202050(4):359-375.  

Density 1.87g/cm3
Melting Point >300ºC(lit.)
Molecular Formula C5H4N4O3
Molecular Weight 170.09700
Exact Mass 170.02200
PSA 114.37000
Index of Refraction 1.721
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport