579475-18-6
579475-18-6 structure
- Name: Orvepitant
- Chemical Name: (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
- CAS Number: 579475-18-6
- Molecular Formula: C31H35F7N4O2
- Molecular Weight: 628.62400
- Create Date: 2017-02-16 18:09:24
- Modify Date: 2023-01-14 13:33:45
-
Orvepitant (GW823296) is a potent and selective, brain penetrant NK1 receptor antagonist with pKi of 10.2.
| Name | (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide |
|---|---|
| Synonyms |
UNII-IIU6V0W3JD
Orvepitant |
| Molecular Formula | C31H35F7N4O2 |
|---|---|
| Molecular Weight | 628.62400 |
| Exact Mass | 628.26500 |
| PSA | 47.10000 |
| LogP | 6.61050 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
