Name | Harpagide |
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Synonyms |
4a,5,7-Trihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl hexopyranoside
einecs 230-050-0 Hexopyranoside, 1,4a,5,6,7,7a-hexahydro-4a,5,7-trihydroxy-7-methylcyclopenta[c]pyran-1-yl |
Description | Harpagide is a class of iridoid glycoside isolated from Scrophularia cryptophila and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2]. |
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Related Catalog | |
In Vitro | Harpagide shows cytotoxic activity over 50% in a concentration of 90 μg/mL, Harpagide on the A431 and HeLa cell lines. The cytotoxic effect of Harpagide on the MCF7 cell line in a concentration of 90 μg/mL[3]. |
References |
Density | 1.7±0.1 g/cm3 |
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Boiling Point | 637.1±55.0 °C at 760 mmHg |
Molecular Formula | C15H24O10 |
Molecular Weight | 364.345 |
Flash Point | 339.1±31.5 °C |
Exact Mass | 364.136932 |
PSA | 169.30000 |
LogP | -3.69 |
Vapour Pressure | 0.0±4.3 mmHg at 25°C |
Index of Refraction | 1.663 |
Safety Phrases | 24/25 |
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Precursor 1 | |
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DownStream 0 |