Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Butaxamine
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: Butaxamine
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Butoxamin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2922-20-5

2922-20-5 structure

2922-20-5 structure

Name: Butoxamin
Chemical Name: 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
CAS Number: 2922-20-5
Molecular Formula: C₁₅H₂₅NO₃
Molecular Weight: 267.36400
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2016-01-18 03:14:46
Modify Date: 2024-01-16 10:24:07
Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity[1].

Name	2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
Synonyms	Butaxaminum Butaxamina Butaxamin Butaxamine

Description	Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Metabolic Disease
Target	β2 adrenoceptor
In Vivo	Butaxamine (0.1, 1, 10 mg/kg; p.o.; once daily for 12 weeks) 增加大鼠的骨量指数以及强度和韧性的生物力学参数[1]。 Animal Model: Seven-week-old male SHR/Izm and WKY/Izm rats[1] Dosage: 0.1, 1, 10 mg/kg Administration: P.o.; once daily for 12 weeks Result: Prevented a decrease in bone mass and an increase in biomechanical fragility developing in SHR, suppressed both a decrease in bone formation and an increase in bone resorption in SHR.
References	[1]. Arai M, et al. Dose effects of butoxamine, a selective β2-adrenoceptor antagonist, on bone metabolism in spontaneously hypertensive rat. Eur J Pharmacol. 2013 Feb 15;701(1-3):7-13.

Density	1.027g/cm3
Boiling Point	391ºC at 760 mmHg
Molecular Formula	C₁₅H₂₅NO₃
Molecular Weight	267.36400
Flash Point	190.3ºC
Exact Mass	267.18300
PSA	50.72000
LogP	2.90470
Vapour Pressure	8.18E-07mmHg at 25°C
Index of Refraction	1.506

HS Code	2922509090

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%