53839-71-7

53839-71-7 structure

Name: Viaminate
Chemical Name: ethyl 4-[[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoyl]amino]benzoate
CAS Number: 53839-71-7
Molecular Formula: C₂₉H₃₇NO₃
Molecular Weight: 447.61
Catalog: API Special medicine Dermatology medication
Create Date: 2018-03-07 08:00:00
Modify Date: 2024-01-09 10:49:53
Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.

Name	ethyl 4-[[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoyl]amino]benzoate
Synonyms	N-(4-(Ethoxycarbonyl)phenyl)retinamide viaminate 4-(Ethoxycarbophenyl)retinamide 4-(Carboethoxyphenyl)retinamide retinamide ethyl benzoate Retinamide,N-(4-(ethoxycarbonyl)phenyl)

Description	Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Viaminate is an amide compound formed by Tretinoin and Ethyl p-aminobenzoate, in which the end group of Tretinoin is transformed into amide and ester chain[1].
References	[1]. Zhang H, et al. Fatal Hepatotoxicity Due to Viaminate. Am J Med Sci. 2018 Jul;356(1):84-86.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982

Hazard Codes	Xi