72025-60-6
72025-60-6 structure
- Name: Leukotriene C4
- Chemical Name: leukotriene C4
- CAS Number: 72025-60-6
- Molecular Formula: C30H47N3O9S
- Molecular Weight: 625.774
- Create Date: 2018-06-23 17:55:40
- Modify Date: 2024-01-02 15:55:16
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Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity.
| Name | leukotriene C4 |
|---|---|
| Synonyms |
L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-glycine
7,9,11,14-Eicosatetraenoic acid, 6-[[(2R,3Z)-2-[[(1E,4S)-4-amino-4-carboxy-1-hydroxybutylidene]amino]-3-[(carboxymethyl)imino]-3-hydroxypropyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)- L-γ-Glutamyl-S-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxy-6,8,10,13-nonadecatetraen-5-yl]-L-cysteinylglycine leukotriene C1 Leukotriene C4 leucotriene C-1 Leukotriene C4 Lipid Maps MS Standard Leucotriene C4 (5S,6R,7E,9E,11Z,14Z)-6-({(2R,3Z)-2-{(E)-[(4S)-4-Amino-4-carboxy-1-hydroxybutylidene]amino}-3-[(carboxymethyl)imino]-3-hydroxypropyl}sulfanyl)-5-hydroxy-7,9,11,14-icosatetraenoic acid LTC4 Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl- leukotrienec MFCD00151079 |
| Description | Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. |
|---|---|
| Target |
Human Endogenous Metabolite |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 974.3±65.0 °C at 760 mmHg |
| Molecular Formula | C30H47N3O9S |
| Molecular Weight | 625.774 |
| Flash Point | 543.1±34.3 °C |
| Exact Mass | 625.303284 |
| PSA | 241.65000 |
| LogP | 4.35 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.564 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
|
| Hazard Codes | F: Flammable;T: Toxic; |
|---|---|
| Risk Phrases | 11-23/24/25-39/23/24/25 |
| Safety Phrases | 36/37-45 |
| RIDADR | UN 1230 3/PG 2 |