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102068-15-5

102068-15-5 structure
102068-15-5 structure
  • Name: PGLa
  • Chemical Name: gly-met-ala-ser-lys-ala-gly-ala-ile-ala-gly-lys-ile-ala-lys-val-ala-leu-lys-ala-leu-nh2
  • CAS Number: 102068-15-5
  • Molecular Formula: C88H162N26O22S
  • Molecular Weight: 1968.45000
  • Catalog: Peptides
  • Create Date: 2016-08-12 15:35:21
  • Modify Date: 2024-01-05 23:43:18
  • PGLa is an antimicrobial peptide. PGLa is known to be bacteriostatic against both Gram-positive and Gram-negative bacteria.

Name gly-met-ala-ser-lys-ala-gly-ala-ile-ala-gly-lys-ile-ala-lys-val-ala-leu-lys-ala-leu-nh2
Synonyms PGLa
Description PGLa is an antimicrobial peptide. PGLa is known to be bacteriostatic against both Gram-positive and Gram-negative bacteria.
Related Catalog
Target

Anti-bacteria[1]

In Vitro PGLa is known to be bacteriostatic against both Gram-positive and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Streptococcus pyogenes, and Staphylococcus aureus), without much selectivity between the two types of bacterial cells. PGLa is synthesized as a native (the wild type) peptide and as a mutant with a norleucine instead of methionine at position 2Met (designated PGLa(Nle)).
References

[1]. Radchenko DS, et al. Does a methionine-to-norleucine substitution in PGLa influence peptide-membrane interactions? Biochim Biophys Acta. 2016 Sep;1858(9):2019-27.

Molecular Formula C88H162N26O22S
Molecular Weight 1968.45000
Exact Mass 1967.21000
PSA 800.72000
LogP 4.65010
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport