61128-08-3

61128-08-3 structure
61128-08-3 structure
  • Name: Succinic acid-13C2
  • Chemical Name: Succinic acid-2,3-13C2
  • CAS Number: 61128-08-3
  • Molecular Formula: C4H6O4
  • Molecular Weight: 120.07300
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-06-28 19:36:23
  • Modify Date: 2024-01-11 19:43:29
  • Succinic acid-13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

Name Succinic acid-2,3-13C2
Synonyms Butanedioic acid-2,3-13C2
<2,3-13C2>Bernsteinsaeure
1,4-butanedioic acid-2,3-13C2
MFCD00145336
butanedioic-2,3-13C2 acid
<2,3-13C2>succinic acid
Succinic Acid (2,3-13C2, 99%)
Description Succinic acid-13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10.  

[3]. A T JOHNS, et al. The production of propionic acid by decarboxylation of succinic acid in a bacterial fermentation. Biochem J. 194842(1):ii.  

[4]. Si Wei Chen, Anxiolytic-like effect of succinic acid in mice. Life Sci. 2003 Nov 773(25):3257-64.  

Density 1.408g/cm3
Boiling Point 235ºC
Melting Point 187-190ºC(lit.)
Molecular Formula C4H6O4
Molecular Weight 120.07300
Exact Mass 120.03300
PSA 74.60000
Index of Refraction 1.477
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 36/37/38-41
Safety Phrases 26-36
RIDADR NONH for all modes of transport

~64%

61128-08-3 structure

61128-08-3

Literature: Cane; Liang; Hasler Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7274 - 7281

~%

61128-08-3 structure

61128-08-3

Literature: Kushner; Weinhouse Journal of the American Chemical Society, 1949 , vol. 71, p. 3558

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61128-08-3 structure

61128-08-3

Literature: Ashworth, Doreen M.; Robinson, John A.; Turner, David L. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1719 - 1728

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61128-08-3 structure

61128-08-3

Literature: Franke, Wilfried; Schwarz, Helmut; Thies, Helga; Chandrasekhar, Jayaraman; Raque' Schleyer, Paul von; et al. Chemische Berichte, 1981 , vol. 114, # 8 p. 2808 - 2824