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54110-25-7

54110-25-7 structure
54110-25-7 structure
  • Name: Pirozadil
  • Chemical Name: [6-[(3,4,5-trimethoxybenzoyl)oxymethyl]pyridin-2-yl]methyl 3,4,5-trimethoxybenzoate
  • CAS Number: 54110-25-7
  • Molecular Formula: C27H29NO10
  • Molecular Weight: 527.52000
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-05-23 08:00:00
  • Modify Date: 2024-01-08 08:19:15
  • Pirozadil is a hypolipidemic agent.

Name [6-[(3,4,5-trimethoxybenzoyl)oxymethyl]pyridin-2-yl]methyl 3,4,5-trimethoxybenzoate
Synonyms 2,6-Pyridinediyldimethylene bis(3,4,5-trimethoxybenzoate)
2,6-Pyridinediylbis(methylene) 3,4,5-trimethoxybenzoate
Benzoic acid,3,4,5-trimethoxy-,2,6-pyridinediylbis(methylene) ester
EINECS 258-978-1
Pirozadil
722 d
Pirozadilum [INN-Latin]
Pemix
2,6-Pyridinedimethanol bis(3,4,5-trimethoxybenzoate)
Description Pirozadil is a hypolipidemic agent.
Related Catalog
In Vivo Pirozadil is a hypolipidemic agent. Pirozadil's effect on increasing cerebral blood flow is almost equal to that of papaverine, less than that of nicardipine and much greater than that of the other hypolipidemic/antiatherogenic drugs, nicotinic acid and pyridinol carbamate. Pirozadil is also shown to significantly diminish vascular cerebral resistance to a much greater degree than nicotinic acid and pyridinol carbamate[1].
References

[1]. Roca J, et al. Effect of pirozadil on cerebral blood flow in anesthetized dogs. Methods Find Exp Clin Pharmacol. 1981 Nov-Dec;3(6):397-401.

Density 1.244g/cm3
Boiling Point 594ºC at 760mmHg
Molecular Formula C27H29NO10
Molecular Weight 527.52000
Flash Point 313ºC
Exact Mass 527.17900
PSA 120.87000
LogP 3.84720
Index of Refraction 1.559
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DI0878200
CHEMICAL NAME :
Benzoic acid, 3,4,5-trimethoxy-, 2,6-pyridinediylbis(methylene) ester
CAS REGISTRY NUMBER :
54110-25-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H29-N-O10
MOLECULAR WEIGHT :
527.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AFTOD7 Archivos de Farmacologia y Toxicologia. (Universidad Complutense, Facultad de Medicina, Departamento Coordinado de Farmacologia, Ciudad Universitaria, Madrid 3, Spain) V.1- 1975- Volume(issue)/page/year: 6,41,1980
HS Code 2933399090
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%