73981-34-7

73981-34-7 structure

Name: Kamebakaurine
Chemical Name: kamebakaurin
CAS Number: 73981-34-7
Molecular Formula: C₂₀H₃₀O₅
Molecular Weight: 350.44900
Catalog: Research Areas Cancer
Create Date: 2016-09-21 19:55:38
Modify Date: 2024-01-02 19:30:49
Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].

Name	kamebakaurin
Synonyms	1,7,14,20-Tetrahydroxykaur-16-en-15-one (1alpha,7alpha,14R) Kaur-16-en-15-one,1,7,14,20-tetrahydroxy-,(1alpha,7alpha,14R)

Description	Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
References	[1]. Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20.