Kamebakaurine

Modify Date: 2024-01-02 19:30:49

Kamebakaurine Structure
Kamebakaurine structure
Common Name Kamebakaurine
CAS Number 73981-34-7 Molecular Weight 350.44900
Density 1.3g/cm3 Boiling Point 563.5ºC at 760 mmHg
Molecular Formula C20H30O5 Melting Point 7ºC
MSDS N/A Flash Point 308.6ºC

 Use of Kamebakaurine


Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].

 Names

Name kamebakaurin
Synonym More Synonyms

 Kamebakaurine Biological Activity

Description Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].
Related Catalog
References

[1]. Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20.

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 563.5ºC at 760 mmHg
Melting Point 7ºC
Molecular Formula C20H30O5
Molecular Weight 350.44900
Flash Point 308.6ºC
Exact Mass 350.20900
PSA 97.99000
LogP 1.03920
Index of Refraction 1.601

 Synonyms

1,7,14,20-Tetrahydroxykaur-16-en-15-one (1alpha,7alpha,14R)
Kaur-16-en-15-one,1,7,14,20-tetrahydroxy-,(1alpha,7alpha,14R)